{
  "record": {
    "id": "20fa34a01803",
    "label": "IndiPGx-Pop p080",
    "cohort": "india-sim",
    "source": "report",
    "createdAt": "2026-10-30T13:53:46.087Z"
  },
  "calls": [
    {
      "gene": "NUDT15",
      "diplotype": "*3/*1",
      "phenotype": "Intermediate Metabolizer",
      "source": "OUTSIDE"
    },
    {
      "gene": "TPMT",
      "diplotype": "*1/*1",
      "phenotype": "Normal Metabolizer",
      "source": "OUTSIDE"
    }
  ],
  "extract": {
    "genes": [
      {
        "activityScore": "",
        "diplotype": "*1/*1",
        "gene": "TPMT",
        "phenotype": "Normal metabolizer",
        "verbatim": "TPMT *2, *3A, *3B, *3C *1/*1 Normal metabolizer"
      },
      {
        "activityScore": "",
        "diplotype": "*3/*1",
        "gene": "NUDT15",
        "phenotype": "Intermediate metabolizer",
        "verbatim": "NUDT15 rs116855232 (*3) *3/*1 Intermediate metabolizer"
      }
    ],
    "labName": "Synthetic Genomics Lab (Kochi)",
    "methodNotes": "Method: targeted genotyping by real-time PCR. Only the listed variants are assayed; variants outside this panel cannot be excluded.",
    "patientRef": "",
    "reportDate": "3 Oct 2026",
    "testedVariants": [
      {
        "gene": "TPMT",
        "variant": "*2"
      },
      {
        "gene": "TPMT",
        "variant": "*3A"
      },
      {
        "gene": "TPMT",
        "variant": "*3B"
      },
      {
        "gene": "TPMT",
        "variant": "*3C"
      },
      {
        "gene": "NUDT15",
        "variant": "rs116855232 (*3)"
      }
    ],
    "warnings": [
      "Only the listed variants are assayed; variants outside this panel cannot be excluded.",
      "TPMT *1/*1 reflects only tested variants *2, *3A, *3B, *3C; untested variants cannot be excluded."
    ]
  },
  "quality": {
    "identifierRemoved": true,
    "unread": [],
    "coverage": [
      {
        "gene": "NUDT15",
        "variant": "*3",
        "stated": true,
        "why": "Main NUDT15 risk allele, ~7-11% in Indians (PMID 29470173)"
      },
      {
        "gene": "TPMT",
        "variant": "*3C",
        "stated": true,
        "why": "Most common TPMT variant in South Asians"
      }
    ],
    "warnings": [
      "Only the listed variants are assayed; variants outside this panel cannot be excluded.",
      "TPMT *1/*1 reflects only tested variants *2, *3A, *3B, *3C; untested variants cannot be excluded."
    ]
  },
  "review": null,
  "pharmcat": {
    "version": "3.4.0",
    "data": "2026-07-13-11-40"
  },
  "note": "Research record. Not medical advice."
}